Integrated Respiratory Virus Bulletin, Ireland

ISO Week 41 2026 (05/10/2026-11/10/2026 )

Report prepared on 16/10/2026



This interactive bulletin reports on the latest epidemiology of COVID-19, influenza, respiratory syncytial virus (RSV) and other respiratory viruses (ORVs) in Ireland. HPSC monitors several integrated respiratory virus surveillance systems that are included in this bulletin. This report is currently published fortnightly.

How to use this interactive bulletin

For interactive graphs – data values and labels can be seen by hovering over graph lines or bars. Specific categories can be selected or deselected by clicking on the relevant category in the legend. Readers can skip to specific sections by clicking on the table of contents to the left of the screen.

Data are presented according to the ISO calendar (Monday to Sunday). Case notifications are reported based on the week of each case’s epidemiological date. This date is the earliest available date for the case and is determined using a hierarchical approach based on symptom onset date, lab specimen collection date, lab specimen received date, date of diagnosis and date of notification to HPSC. Case notification data reported for the most recent week may underestimate true disease activity, as some cases may not yet have been notified.


1 Key messages

  • Influenza activity increased but remains at baseline-low levels overall. RSV activity has remained stable at baseline levels in recent weeks. COVID-19 activity was stable and remained at low-moderate levels.
  • Rhino/enteroviruses detections were at high levels, particularly in paediatrics.
  • Vaccination/immunisation remains one of the most effective ways to reduce severe illness from influenza, RSV, and COVID-19. Strong surveillance immunisation programmes and healthcare system readiness (including Infection Prevention Control) are key to protecting public health.

1.1 Summary for most recent week

Syndromic surveillance

The sentinel GP Acute Respiratory Infection (ARI) clinical consultation rate increased and was above baseline levels in ISO week 41 2026 at 86.5/100,000 population. The highest rate was in those aged 0-4 years at 352.4/100,000 population. The sentinel GP influenza-like-illness (ILI) consultation rate increased but remained below baseline at 10.2/100,000 population in week 41. SARS-CoV-2 positivity decreased to 11%. Rhino/enterovirus positivity has remained at high levels in recent weeks, increasing to 36% in week 41. Influenza, RSV and all other seasonal respiratory pathogen test positivity levels were below the 10% baseline threshold. The percentage of GP Out-Of-Hours (GP-OOH) calls for self-reported cough increased while flu calls decreased; cough calls were above baseline at 18% and flu calls remain below baseline in week 41.

COVID-19

COVID-19 activity remains at low-moderate levels. In week 41 2026, the overall incidence was 3.9/100,000 population, and highest in those aged ≥80 years. There were 202 COVID-19 cases, 61 Emergency Department (non-hospitalised) cases and 93 hospitalisations notified in week 41, with stable trends for all of these indicators in recent weeks. ICU admissions and deaths have remained low. There have been no ICU admissions and three deaths reported for this season to date, seven ICU cases were reported between weeks 21 and 39. COVID-19 hospital bed occupancy* has been stable during recent weeks. XFG was the predominant SARS-CoV-2 variant, accounting for 51% of specimens sequenced in the last ten weeks.

Influenza

Influenza activity has increased slightly in recent weeks but remains at baseline-low levels overall. In week 41 2026, the overall incidence was 2.1/100,000 population and highest in those aged ≥80 years of age. There were 106 influenza cases, 53 Emergency Department (non-hospitalised) and 28 hospitalisations notified in week 41, with small but gradually increasing trends for all of these indicators in recent weeks. There have been no ICU admissions and two deaths reported for this season to date, and 11 ICU cases were reported between weeks 21 and 39. Influenza hospital bed occupancy* has remained stable and low in recent weeks. Influenza A(H1)pdm09 accounted for the majority of subtyped influenza A viruses during the season to date.

RSV

RSV activity remained stable at baseline levels in recent weeks. In week 41 2026, the overall incidence of RSV was 0.2/100,000 population and highest in those aged <1 year. There were eight RSV cases, five Emergency Department (non-hospitalised) cases and three hospitalisations notified in week 41. There have been no ICU admissions or deaths reported for the season to date, two ICU cases were reported between weeks 21 and 39. RSV hospital bed occupancy* has remained low and stable.

Severe Acute Respiratory Infection (SARI)

In ISO week 41 2026, SARI activity was stable and remained at low levels in Ireland; 88 SARI cases were reported from the four sentinel hospital sites. Test positivity for SARS-CoV-2, RSV and influenza was below 10%.

Outbreaks

Acute respiratory infection (ARI) outbreak notifications have been increasing overall since week 31 2026. There were 32 ARI outbreaks notified in health and care settings during week 41 2026 (18 COVID-19, three influenza and 11 other ARI). Of these 32 outbreaks, 19 were in nursing homes, nine were in hospitals, two were in community hospitals/long-stay units and two were in residential institutions.

Excess mortality

The latest HPSC excess mortality analysis of all registered deaths in Ireland up to October 11, 2026 (ISO week 41 2026) using the standardised European EuroMOMO algorithm shows that there has been no overall excess all-cause mortality reported for the entire Irish population (all ages) during the 2026 summer period to date (week 18 2026 onwards)

*Since 30th September 2026, bed occupancy data are incomplete, due to industrial action.


2 Syndromic and case surveillance

2.1 Sentinel GP Acute Respiratory Infection (ARI) and Influenza-like-illness (ILI) surveillance

2.1.1 Sentinel GP ARI and ILI

1: Sentinel GP ARI and ILI consultation rates per 100,000 population overall (with associated number of influenza, RSV and SARS-CoV-2 positive sentinel GP ARI specimens) in Ireland, from week 40 2025 to week 41 2026. Data source: Sentinel GP surveillance system and National Virus Reference Laboratory (NVRL).


2.1.2 Sentinel GP ARI by age group

2: Sentinel GP ARI consultation rates by age-group in Ireland, from week 40 2025 to week 41 2026. Data source: Sentinel GP surveillance system.


2.2 GP out-of-hours surveillance


3: Percentage of calls to GP out-of-hours services for self-reported cough and self-reported influenza in Ireland for all ages and by age-group, by week of call, from week 40 2025 to week 41 2026. Data source: Participating GP Out-of-Hours services in Ireland.


2.3 Confirmed cases

2.3.1 Laboratory-confirmed cases: COVID-19, influenza, RSV

4: Number of notified cases of laboratory-confirmed COVID-19, influenza and RSV by Epi week in Ireland, between week 40 2025 and week 41 2026. Data source: CIDR

Note: Grey shading indicates that activity reported for the most recent week may underestimate true disease activity, as some cases may not yet have been notified



2.3.2 COVID-19 seasonal trends

5: Number of notified cases of laboratory-confirmed COVID-19 by week in Ireland, between Epi week 40 2023 and week 41 2026. Data source: CIDR

Please note: where there is a 53 week year, the average of week 52 and week 53 is taken. The week labelled week 52 2025 in Figures 5, 6 and 7 have a total number of confirmed cases which is the average of the total for weeks 52 and 53 2025


2.3.3 Influenza seasonal trends

6: Number of notified cases of laboratory-confirmed influenza by week in Ireland, between Epi week 40 2023 and week 41 2026. Data source: CIDR

Please note: where there is a 53 week year, the average of week 52 and week 53 is taken. The week labelled week 52 2025 in Figures 5, 6 and 7 have a total number of confirmed cases which is the average of the total for weeks 52 and 53 2025


2.3.4 RSV seasonal trends

7: Number of notified cases of laboratory-confirmed RSV by Epi week in Ireland, between week 40 2023 and week 41 2026. Data source: CIDR

Please note: where there is a 53 week year, the average of week 52 and week 53 is taken. The week labelled week 52 2025 in Figures 5, 6 and 7 have a total number of confirmed cases which is the average of the total for weeks 52 and 53 2025


Table 1: Number and incidence of notified laboratory-confirmed cases of COVID-19, influenza and RSV by age, sex and HSE Health Region Ireland, week 41 2026. Data source: CIDR

Number of cases (incidence per 100,000 population)

All pathogens

COVID-19

Influenza

RSV

Cases

316 (6.1)

202 (3.9)

106 (2.1)

8 (0.2)

Age groups (years)

<1

10 (17.3)

7 (12.1)

2 (3.5)

1 (1.7)

1-4

15 (6.3)

5 (2.1)

7 (2.9)

3 (1.3)

5-14

10 (1.4)

2 (0.3)

8 (1.1)

0 (0.0)

15-44

55 (2.7)

35 (1.7)

19 (0.9)

1 (0.0)

45-64

46 (3.6)

24 (1.9)

21 (1.6)

1 (0.1)

65-79

93 (15.6)

60 (10.1)

31 (5.2)

2 (0.3)

≥80

87 (48.1)

69 (38.1)

18 (9.9)

0 (0.0)

Median age (IQR)

70 (39-80)

74 (48-82)

62 (32-75)

19 (2-62)

Sex

Male

144 (5.7)

95 (3.7)

46 (1.8)

3 (0.1)

Female

172 (6.6)

107 (4.1)

60 (2.3)

5 (0.2)

HSE Health Regions

Dublin and North East

73 (6.1)

45 (3.8)

28 (2.4)

0 (0)

Dublin and Midlands

42 (3.9)

26 (2.4)

14 (1.3)

2 (0.2)

Dublin and South East

39 (4)

29 (3)

10 (1)

0 (0)

South West

54 (7.3)

35 (4.7)

19 (2.6)

0 (0)

Mid West

36 (8.7)

26 (6.3)

10 (2.4)

0 (0)

West and North West

71 (9.3)

40 (5.3)

25 (3.3)

6 (0.8)


An overview of the characteristics of all cases reported since the start of the season is presented in Appendix A1.



8: Incidence of notified cases of laboratory-confirmed COVID-19, influenza and RSV by HSE Health Region for the last 12 weeks by Epi week, from week 30 2026 to week 41 2026. Data source: CIDR


9: Age and sex-specific incidence of notified cases of laboratory-confirmed COVID-19, influenza and RSV in Ireland, from week 40 2026 to week 41 2026. Data source: CIDR

Note: The scale on the x-axis may differ by pathogen, to account for differences in the number of cases notified for each pathogen.


10: Incidence of notified cases of laboratory-confirmed COVID-19, influenza and RSV in Ireland, by age group and Epi week, from week 40 2025 to week 41 2026. Data source: CIDR


3 Severity and impact

3.1 Sentinel Severe Acute Respiratory Infection (SARI) surveillance

3.1.1 SARI case numbers by site

11: Number of SARI hospitalised cases by week of hospital admission in Ireland, from week 40 2025 to week 41 2026. Data source: Sentinel SARI surveillance system.

3.1.2 Incidence of SARI hospital admissions

12: SARI age-specific incidence rates per 100 hospital admissions by week of hospital admission in Ireland, from week 40 2025 to week 41 2026. Data source: Sentinel SARI surveillance system.

*SARI cases are recruited from emergency department admissions only in SVUH, SJH and UHL. In CHI-C cases are recruited from emergency department and non-emergency department routes (e.g. transfer from other hospitals, direct admission to speciality wards), excluding day cases and elective admissions.


13: Percentage of SARI cases with a positive laboratory test result for SARS-CoV-2, influenza or RSV by week of hospital admission in Ireland, from week 40 2025 to week 41 2026. Data source: Sentinel SARI surveillance system.


3.2 Emergency department cases

3.2.1 Incidence of emergency department cases

14: Incidence of emergency department cases of laboratory-confirmed COVID-19, influenza and RSV by Epi week in Ireland, from week 40 2025 to week 41 2026. Data source: CIDR

Note: Grey shading indicates that activity reported for the most recent week may underestimate true disease activity, as some cases may not yet have been notified


3.2.2 Number of emergency department cases


15: Number of emergency department cases of laboratory-confirmed COVID-19, influenza and RSV by Epi week in Ireland, from week 40 2025 to week 41 2026. Data source: CIDR

Note: Grey shading indicates that activity reported for the most recent week may underestimate true disease activity, as some cases may not yet have been notified


3.3 Hospital admissions

3.3.1 Incidence of hospitalised cases


16: Incidence of hospitalised cases of laboratory-confirmed COVID-19, influenza and RSV by Epi week in Ireland, from week 40 2025 to week 41 2026. Data source: CIDR

Note: Grey shading indicates that activity reported for the most recent week may underestimate true disease activity, as some cases may not yet have been notified


3.3.2 Number of hospitalised cases


17: Number of hospitalised cases of laboratory-confirmed COVID-19, influenza and RSV by Epi week in Ireland, from week 40 2025 to week 41 2026. Data source: CIDR

Note: Grey shading indicates that activity reported for the most recent week may underestimate true disease activity, as some cases may not yet have been notified


Table 2: Number and incidence of hospitalised cases of laboratory-confirmed COVID-19, influenza and RSV by age, sex and HSE Health Region Ireland, week 41 2026. Data source: CIDR

Number of cases (incidence per 100,000 population)

All pathogens

COVID-19

Influenza

RSV

Cases

124 (2.4)

93 (1.8)

28 (0.5)

3 (0.1)

Age groups (years)

<1

2 (3.5)

2 (3.5)

0 (0.0)

0 (0.0)

1-4

8 (3.4)

3 (1.3)

4 (1.7)

1 (0.4)

5-14

2 (0.3)

0 (0.0)

2 (0.3)

0 (0.0)

15-44

15 (0.7)

11 (0.5)

3 (0.1)

1 (0.0)

45-64

16 (1.2)

11 (0.9)

5 (0.4)

0 (0.0)

65-79

40 (6.7)

30 (5.0)

9 (1.5)

1 (0.2)

≥80

41 (22.6)

36 (19.9)

5 (2.8)

0 (0.0)

Median age (IQR)

74 (58-81)

77 (62-82)

64 (27-76)

35 (19-51)

Sex

Male

59 (2.3)

44 (1.7)

14 (0.6)

1 (0.0)

Female

65 (2.5)

49 (1.9)

14 (0.5)

2 (0.1)

HSE Health Regions

Dublin and North East

20 (1.7)

16 (1.3)

4 (0.3)

0 (0)

Dublin and Midlands

10 (0.9)

8 (0.7)

1 (0.1)

1 (0.1)

Dublin and South East

20 (2.1)

19 (2)

1 (0.1)

0 (0)

South West

20 (2.7)

13 (1.8)

7 (0.9)

0 (0)

Mid West

19 (4.6)

13 (3.1)

6 (1.5)

0 (0)

West and North West

35 (4.6)

24 (3.2)

9 (1.2)

2 (0.3)


An overview of the characteristics of all hospitalised cases reported since the start of the season is presented in Appendix A2.


18: Age and sex-specific incidence of hospitalised cases of laboratory-confirmed COVID-19, influenza and RSV in Ireland, from week 40 2026 to week 41 2026. Data source: CIDR

Please note that the scale on the x-axis may differ by pathogen, to account for differences in the number of cases notified for each pathogen.


19: Incidence of hospitalised cases of laboratory-confirmed COVID-19, influenza and RSV by age group in Ireland, from week 40 2025 to week 41 2026. Data source: CIDR


3.3.3 Bed occupancy in acute inpatient settings

3.3.3.1 Number of acute hospital beds occupied last 30 days

20: Daily number of acute hospital beds occupied by patients with laboratory-confirmed COVID-19, influenza and RSV in Ireland in the last 30 days. Data source: HSE Planning and Performance Unit

Note: Since 30th September 2026 these data are incomplete, due to industrial action.


3.3.3.2 Number of acute hospital beds occupied week 40 2025 onwards

21: Daily number of acute hospital beds occupied by patients with laboratory-confirmed COVID-19, influenza and RSV in Ireland from week 40 2025 to week 41 2026. Data source: HSE Planning and Performance Unit

Note: Since 30th September 2026 these data are incomplete, due to industrial action.


3.4 Intensive Care Unit (ICU) admissions


22: Number of ICU admissions due to laboratory-confirmed COVID-19, influenza and RSV by week of admission to ICU in Ireland, week 40 2025 to week 41 2026. Data source: CIDR


Table 3: Number and incidence of ICU admissions due to COVID-19, influenza and RSV in Ireland by week of admission to ICU, week 41 2026, and from week 40 2026 to week 41 2026. Data source: CIDR

Week 41, 2026

Week 40, 2026 to week 41, 2026

Number of ICU admissionsa

ICU admissions per 1,000 hospitalisations

% of hospitalised cases admitted to ICU

Number of ICU admissions

ICU admissions per 1,000 hospitalisations

% of hospitalised cases admitted to ICU

COVID-19

0

0

0

0

0

0

Influenza

0

0

0

0

0

0

RSV

0

0

0

0

0

0

aICU admissions include all cases admitted to ICU due to COVID-19, influenza and RSV


3.5 Mortality

3.5.1 Deaths among confirmed cases


23: Number of COVID-19, influenza and RSV deaths by week of death in Ireland, week 40 2025 to week 41 2026. Data source: CIDR


Table 4: Number and incidence of COVID-19, influenza and RSV deaths in Ireland, from week 40 2026 to week 41 2026. Data source: CIDR

COVID-19

Influenza

RSV

Age (years)

Number of deaths

Incidence per 100,000 population

Number of deaths

Incidence per 100,000 population

Number of deaths

Incidence per 100,000 population

<65

2

0.0

0

0.0

0

0

≥65

1

0.1

2

0.3

0

0

Total

3

0.1

2

0.0

0

0


4 Outbreaks


24: Number of COVID-19, influenza, RSV and other ARI outbreaks reported in health and care settings by week outbreak reported in Ireland, from week 40 2025 to week 41 2026. Data source: CIDR


Table 5: Number of COVID-19, influenza, RSV and other ARI outbreaks reported by setting in Ireland, week 41 2026 and from week 40 2026 to week 41 2026. Data source: CIDR

Week 41 2026

Outbreak location

COVID-19

Influenza

RSV

ARI

Total week 41, 2026

Total week 40, 2026 to week 41, 2026

Comm. hosp/long-stay unit

2

0

0

0

2

2

Hospital

6

2

0

1

9

26

Nursing home

8

1

0

10

19

40

Other healthcare service

0

0

0

0

0

0

Residential institution

2

0

0

0

2

2

Total health care settings

18

3

0

11

32

70

Total non health care settings

0

0

0

0

0

0

Total

18

3

0

11

32

70


25: Number of COVID-19, influenza, RSV and other ARI outbreaks by HSE Health Region, Ireland, week 41 2026. Data source: CIDR


5 Virology and genomic surveillance

5.1 Virus test positivity and dominant virus types/subtypes in circulation


Table 6: Number and percentage positive SARS-CoV-2, influenza and RSV specimens by surveillance source Ireland, week 41 2026. Data source: NVRL.

SARS-CoV-2

Influenza

RSV

Surveillance system

Total tested

Total positive

% positive

Total positive

% positive

Total positive

% positive

NVRL Sentinel GP ARI

113

12

10.6

9

8.0

0

0

NVRL non-sentinel respiratory

225

27

12.0

3

1.3

0

0


26: Sentinel GP ARI specimens and non-sentinel respiratory specimen test positivity for SARS-CoV-2, influenza, RSV and other respiratory viruses by week of specimen collection in Ireland, week 21 2026 to week 41 2026. hMPV=human metapneumovirus; PIV = parainfluenza viruses. Data source: NVRL.


27: Number of sentinel GP ARI and non-sentinel respiratory influenza positive specimens and laboratory-confirmed influenza notifications by influenza type/sub-type and by week of specimen collection in Ireland, week 40 2025 to week 41 2026. Data source: NVRL, CIDR


Underlying data on the total number of tests, total number of positives and percentage positive by week and for the season to date for each virus for both sentinel and non-sentinel specimens are presented in Appendix A3, Appendix A4, Appendix A5, Appendix A6


5.2 SARS-CoV-2 genomic data


28: SARS-CoV-2 whole genome sequencing results by week of specimen collection in Ireland, from week 40 2025 to week 37 2026


Note: There is currently a lag time of 4-8 weeks between a case being notified, selected for sequencing and sequencing being completed. This may be longer when there is a lower number of cases due to batching of specimens. Therefore, the percentage of cases notified in this time period who are ultimately sequenced will be higher than reported here.



8 Technical notes

General

Data are provisional and subject to ongoing review, validation and update. As a result, figures in this report may differ from previously published figures.

Please note that the excess mortality data are provisional due to the time delay with death registration in Ireland. A country-specific adjustment function was applied to correct for the typical delay in registrations of deaths in Ireland. Nonetheless, estimates of excess mortality for the most recent weeks are reported with some uncertainty and should be interpreted with caution.

Definitions

The case definitions for COVID-19, influenza and RSV are available here. Only data on laboratory-confirmed cases, including cases diagnosed using near patient molecular tests, are included in this report.

Sentinel GP ARI consultations are consultations to sentinel GP practices for Acute Respiratory Infection (ARI), with ARI defined as sudden onset of symptoms AND at least one of the following four respiratory symptoms: Cough, sore throat, shortness of breath, coryza AND a clinician’s judgement that the illness is due to an infection.

Sentinel GP ILI consultations are consultations to sentinel GP practices for Influenza like illness (ILI), with ILI defined as sudden onset of symptoms AND at least one of the following four respiratory symptoms: Fever or feverishness, malaise, headache, myalgia AND at least one of the following three respiratory symptoms: Cough, sore throat, shortness of breath.

GP out of hours calls refer to calls to GP out of hours services from persons with self-reported clinical symptoms of ‘flu’ or ‘cough’.

Emergency Department cases refer to cases treated in emergency departments, with no indication on CIDR that they have subsequently been admitted to hospital.

Hospitalised cases are inpatients with laboratory-confirmed SARS-CoV-2, influenza or RSV and includes inpatients with incidental infections, where the infection is not the reason for their admission.

Bed occupancy refers to the number of laboratory-confirmed cases admitted to acute inpatient sites at 08:00 hrs on the day of reporting.

A SARI case is defined as a person hospitalised for at least 24 hours with acute respiratory infection and onset of symptoms within 14 days prior to hospital admission, with at least one of the following symptoms: cough, fever, shortness of breath OR sudden onset of anosmia, ageusia or dysgeusia.

The case definition was adapted in Ireland for infants aged <6 months to include increased work of breathing and apnoea as relevant symptoms, the revised definition was applied to cases admitted from week 40 2025. A SARI case refers to an individual patient episode of care.

As of September 2024, ICU admissions for COVID-19, influenza and RSV refer to those admitted to intensive care where COVID-19, influenza or RSV were the primary or contributory cause of admission. Prior to September 2024, ICU admissions for influenza and RSV included all admissions where the patient tested positive for influenza or RSV, irrespective of whether these pathogens were the cause of admission.

COVID-19, influenza and RSV deaths are defined as a death in a person with laboratory-confirmed COVID-19, influenza or RSV infection, see case definitions (this includes cases detected postmortem)

Test Positivity: Positive tests refer to all positive specimens and includes duplicates and individuals who were re-tested.

Outbreaks are defined as two or more cases of acute respiratory infection with the same pathogen (SARS-CoV-2, influenza or respiratory syncytial virus (RSV)) confirmed by a laboratory test or near patient test carried out by a health professional, and where there is reason to consider that these cases may be epidemiologically linked in place and time.

Other Acute Respiratory Infection (ARI) outbreaks are defined as: Two or more cases of acute respiratory infection with onset within five days epidemiologically linked in place. Outbreaks are classified as Suspect ARI outbreaks, where testing has not been completed, is pending or has been negative for Influenza, RSV and SARS-CoV-2. Outbreaks are classified as confirmed if other respiratory pathogens (ORVs), e.g. Rhinovirus, hMPV, Coronavirus OC43 etc are identified via laboratory confirmation. The outbreak data presented in this report includes both confirmed and suspect outbreaks.

Variant working definitions for ‘SARS-CoV-2 variants of concern’ (VOC), ‘SARS-CoV-2 variants of interest’ (VOI) and ‘SARS-CoV-2 variants under monitoring’ (VUM) are available on the WHO website and ECDC website.

Data sources

The Computerised Infectious Disease Reporting (CIDR) system: CIDR is the source of statutory notification data on laboratory-confirmed COVID-19, influenza, RSV (including data on notified, emergency department, hospitalised and ICU cases and data on cases who died) and data on outbreaks.

The type/subtype of laboratory-confirmed influenza notifications are reported on the CIDR system. The number of cases hospitalised and admitted to ICU described in this report relate only to cases notified during this reporting period, with known hospitalisation/ICU status at the time of reporting.

Regional Departments of Public Health currently prioritise the investigation and reporting of outbreaks in settings that benefit most from public health and clinical intervention. The outbreak data reported here focuses on these key settings/groups. These settings include acute hospitals, nursing homes, community hospital/long-stay units, residential institutions (centres for disabilities, centres for older people, children’s/TUSLA residential centres and mental health facilities) and other healthcare settings.

Population denominator data for analyses of CIDR data on notified, emergency department, hospitalised and ICU cases and deaths are taken from Census 2022.

Sentinel GP surveillance system: This includes 100 participating general practices (located in all HSE Health Regions). These practices report electronically on a weekly basis, the number of patients who consulted with acute respiratory infection (ARI) and influenza-like illness (ILI) (identified using International Classification of Primary Care 2 codes R74 and R80). These practices provide overall and age-stratified denominator data on the number of registered patients who have sought care at the practice during the previous three years. The combined patient population in these practices is estimated to be approximately 10% of the national population. Sentinel GPs take a combined nose and throat swab from the first five patients attending their practice each week who meet the ARI case definition and send these to the NVRL for testing.

GP Out-of-hours (GPOOHs) services: Five out of 14 GPOOHs services provide weekly data on the total and age-stratified number of out of hours calls for 1) all reasons, 2) for self-reported cough and 3) for self-reported flu. The denominator for calculations of percentage of calls is the total number of calls for all reasons.

The HSE Performance Management and Improvement Unit (PMIU) provides daily data on bed occupancy (the number of currents inpatients with laboratory-confirmed COVID-19, influenza and RSV).

Severe Acute Respiratory Infections (SARI) surveillance system: SARI cases are identified based on clinical symptoms from new admissions through the Emergency Department in SVUH, SJH and UHL. In CHI-C cases are recruited from emergency department and non-emergency department routes (e.g. transfer from other hospitals, direct admission to speciality wards), excluding day cases and elective admissions.

National Virus Reference Laboratory (NVRL): The NVRL routinely test sentinel GP and non-sentinel respiratory specimens for SARS-CoV-2, influenza, RSV and a panel of other seasonal respiratory viruses (ORV). The NVRL report on influenza type/subtype of sentinel GP ARI and non-sentinel respiratory specimens on a weekly basis.

The SARS-CoV-2 genomic sequencing sampling framework currently focuses on notified COVID-19 cases with severe disease (hospitalisation, ICU admission) and deaths, COVID-19 outbreaks in health and care settings, sentinel surveillance programmes in the community and acute hospitals and targeted sequencing based on public health risk assessment/clinical requests and virological changes e.g. new variant of concern. There is currently a lag time of 4-8 weeks between a COVID-19 case being notified, selected for sequencing and SARS-CoV-2 sequencing being completed. Therefore, the proportion of notified COVID-19 cases notified in this time period from whom specimens are ultimately sequenced will be higher than currently reported here. The HPSC link sequencing results received from laboratories to epidemiological data on COVID-19 cases reported on the CIDR system. This report summarises WGS results and epidemiological data for COVID-19 cases that have been sequenced in Ireland since week 40 2025 (specimen dates between 29/09/2025 and 10/07/2026). The SARS-CoV-2 sequencing results included in this report reflect all data available as of 01/10/2026.


9 Appendix

Appendix Table 1: Number and incidence of notified laboratory-confirmed cases of COVID-19, influenza and RSV by age, sex and HSE Health Region, from week 40 2026, to week 41 2026. Data source: CIDR

Number of cases (incidence per 100,000 population)

All pathogens

COVID-19

Influenza

RSV

Cases

908 (17.6)

575 (11.2)

311 (6.0)

22 (0.4)

Age groups (years)

<1

40 (69.2)

31 (53.6)

6 (10.4)

3 (5.2)

1-4

43 (18.1)

12 (5.1)

19 (8.0)

12 (5.1)

5-14

27 (3.8)

6 (0.8)

21 (2.9)

0 (0.0)

15-44

172 (8.3)

96 (4.6)

74 (3.6)

2 (0.1)

45-64

157 (12.1)

89 (6.9)

65 (5.0)

3 (0.2)

65-79

251 (42.2)

167 (28.1)

82 (13.8)

2 (0.3)

>80

218 (120.4)

174 (96.1)

44 (24.3)

0 (0.0)

Median age (IQR)

66 (37-79)

71 (44-81)

58 (30-75)

2 (1-34)

Sex

Male

419 (16.5)

264 (10.4)

148 (5.8)

7 (0.3)

Female

489 (18.8)

311 (11.9)

163 (6.3)

15 (0.6)

HSE Health Regions

Dublin and North East

203 (17.1)

129 (10.9)

72 (6.1)

2 (0.2)

Dublin and Midlands

156 (14.5)

94 (8.7)

53 (4.9)

9 (0.8)

Dublin and South East

137 (14.1)

98 (10.1)

39 (4)

0 (0)

South West

139 (18.8)

81 (10.9)

58 (7.8)

0 (0)

Mid West

99 (24)

71 (17.2)

28 (6.8)

0 (0)

West and North West

173 (22.8)

101 (13.3)

61 (8)

11 (1.4)


Appendix Table 2: Number and incidence of notified hospitalised laboratory-confirmed cases of COVID-19, influenza and RSV by age, sex and HSE Health Region from week 40 2026 to week 41 2026. Data source: CIDR

Number of cases (incidence per 100,000 population)

All pathogens

COVID-19

Influenza

RSV

Cases

316 (6.1)

234 (4.5)

73 (1.4)

9 (0.2)

Age groups (years)

<1

11 (19.0)

9 (15.6)

2 (3.5)

0 (0.0)

1-4

21 (8.8)

8 (3.4)

8 (3.4)

5 (2.1)

5-14

8 (1.1)

2 (0.3)

6 (0.8)

0 (0.0)

15-44

35 (1.7)

26 (1.3)

7 (0.3)

2 (0.1)

45-64

49 (3.8)

33 (2.6)

15 (1.2)

1 (0.1)

65-79

93 (15.6)

72 (12.1)

20 (3.4)

1 (0.2)

>80

99 (54.7)

84 (46.4)

15 (8.3)

0 (0.0)

Median age (IQR)

72 (49-81)

74 (58-82)

63 (26-77)

3 (1-35)

Sex

Male

152 (6.0)

113 (4.4)

36 (1.4)

3 (0.1)

Female

164 (6.3)

121 (4.6)

37 (1.4)

6 (0.2)

HSE Health Regions

Dublin and North East

53 (4.5)

43 (3.6)

9 (0.8)

1 (0.1)

Dublin and Midlands

35 (3.2)

21 (1.9)

9 (0.8)

5 (0.5)

Dublin and South East

54 (5.6)

49 (5)

5 (0.5)

0 (0)

South West

42 (5.7)

28 (3.8)

14 (1.9)

0 (0)

Mid West

49 (11.9)

35 (8.5)

14 (3.4)

0 (0)

West and North West

83 (10.9)

58 (7.6)

22 (2.9)

3 (0.4)


Appendix Table 3: Number and percentage of test positive Sentinel GP ARI specimens by respiratory virus for the most recent two weeks 40 2026, week 41 2026 and the 2026/2027 season to date. Data source: NVRL.

Week 40 2026 (N = 142)

Week 41 2026 (N = 113)

2026/2027 (N = 255)

Virus

Total positive

% positive

Total positive

% positive

Total positive

% positive

SARS-CoV-2

17

12.0

12

10.6

29

11.4

Influenza virus

16

11.3

9

8.0

25

9.8

Respiratory syncytial virus (RSV)

1

0.7

0

0.0

1

0.4

Rhino/enterovirus

35

24.6

41

36.3

76

29.8

Adenovirus

0

0.0

0

0.0

0

0.0

Bocavirus

0

0.0

0

0.0

0

0.0

Human metapneumovirus (hMPV)

4

2.8

0

0.0

4

1.6

Parainfluenza virus type 1 (PIV-1)

2

1.4

0

0.0

2

0.8

Parainfluenza virus type 2 (PIV-2)

4

2.8

3

2.7

7

2.7

Parainfluenza virus type 3 (PIV-3)

1

0.7

1

0.9

2

0.8

Parainfluenza virus type 4 (PIV-4)

0

0.0

0

0.0

0

0.0


Appendix Table 4: Number and percentage positive NVRL non-sentinel respiratory specimens by respiratory virus, week 40 2026, week 41 2026 and the 2026/2027 season to date. Data source: NVRL.

Week 40 2026 (N = 320)

Week 41 2026 (N = 225)

2026/2027 (N = 545)

Virus

Total positive

% positive

Total positive

% positive

Total positive

% positive

SARS-CoV-2

35

10.9

27

12.0

62

11.4

Influenza virus

16

5.0

3

1.3

19

3.5

Respiratory syncytial virus (RSV)

2

0.6

0

0.0

2

0.4

Rhino/enterovirus

68

21.2

42

18.7

110

20.2

Adenovirus

3

0.9

1

0.4

4

0.7

Bocavirus

0

0.0

0

0.0

0

0.0

Human metapneumovirus (hMPV)

1

0.3

1

0.4

2

0.4

Parainfluenza virus type 1 (PIV-1)

1

0.3

3

1.3

4

0.7

Parainfluenza virus type 2 (PIV-2)

5

1.6

4

1.8

9

1.7

Parainfluenza virus type 3 (PIV-3)

1

0.3

3

1.3

4

0.7

Parainfluenza virus type 4 (PIV-4)

0

0.0

1

0.4

1

0.2


Appendix Table 5: Influenza type and sub-type distribution among sentinel GP ARI and non-sentinel respiratory influenza positive specimens for the most recent two weeks 40 2026, week 41 2026 and the 2026/2027 season to date. Data source: NVRL.

Influenza A

Influenza B

Time period

Specimen source

Total influenza positive

Total

A(H1)pdm09

A(H3)

A(not subtyped)

Total

B Victoria

B (unspecified)

Week 40 2026

Sentinel GP ARI

16

15

10

4

1

1

0

1

Non-sentinel respiratory

16

16

15

1

0

0

0

0

Total

32

31

25

5

1

1

0

1

Week 41 2026

Sentinel GP ARI

9

9

7

2

0

0

0

0

Non-sentinel respiratory

3

3

3

0

0

0

0

0

Total

12

12

10

2

0

0

0

0

Season total

Sentinel GP ARI

25

24

17

6

1

1

0

1

Non-sentinel respiratory

19

19

18

1

0

0

0

0

Total

44

43

35

7

1

1

0

1


Appendix Table 6: RSV type distribution among sentinel GP ARI and non-sentinel respiratory RSV positive specimens for the most recent two weeks 40 2026, week 41 2026 and the 2026/2027 season to date. Data source: NVRL.

Time period

Specimen source

Total RSV positive

RSV A

RSV B

RSV (unspecified)

Week 40 2026

Sentinel GP ARI

1

0

1

0

Non-sentinel respiratory

2

2

0

0

Total

3

2

1

0

Week 41 2026

Sentinel GP ARI

0

0

0

0

Non-sentinel respiratory

0

0

0

0

Total

0

0

0

0

Season total

Sentinel GP ARI

1

0

1

0

Non-sentinel respiratory

2

2

0

0

Total

3

2

1

0